As I mentioned in some of my previous posts, I am a PhD student working on a project aimed at producing human oocytes in vitro. My current focus is on differentiating human iPSCs to ovarian supporting cells to form “ovaroids” to support oocyte development.
I'm not in biology, but I find this interesting as a layman.
I have a couple of questions. If they're too complex to answer, feel free to ignore.
- "[...] eventually men as well, although this will be more difficult." What makes it more difficult?
- What about the other way around, what's the status of spermatogenesis?
>What makes it more difficult?
Getting rid of the Y chromosome and establishing proper female imprinting.
>What about the other way around, what's the status of spermatogenesis?
https://www.nature.com/articles/s41467-020-19350-3
Not quite as advanced as oogenesis. Less effort is being spent on it since sperm are comparatively cheap.